Research
The CLab develops innovative synthetic strategies for the preparation of structurally diverse small molecules inspired by natural products and biologically relevant scaffolds. Our research integrates organic synthesis, medicinal chemistry, and computational chemistry to generate molecular libraries with potential applications in human health.
Our research integrates organic synthesis, medicinal chemistry, and computational chemistry to develop innovative molecular architectures with biological and therapeutic potential. We develop efficient synthetic strategies for the construction and diversification of complex molecules, combining function-oriented synthesis (FOS), skeletal editing, and cascade reactions with the design and optimization of bioactive compounds targeting diseases of high societal impact, particularly breast cancer, Alzheimer’s disease, and cardiovascular disorders. Computational approaches, including molecular docking, density functional theory (DFT), and transition-state (TS) calculations, complement our experimental studies by providing insights into reaction mechanisms and molecular recognition, while guiding the rational design of new molecules. Through the integration of molecular design, synthesis, biological evaluation, and computational analysis, CLab seeks to advance sustainable approaches to modern organic synthesis and accelerate the discovery of molecules with therapeutic potential.